The group was founded by brothers David and Stephen Dewaele in Ghent, Belgium. From the debut album Leave the Story Untold (1996), passing through Much Against Everyone's Advice (1999) and Any Minute Now (2004), the group has slowly turned from rock to dance sounds and close to electronic music from Dancefloor. Evident proof of this is Nite Versions, in which the tracks of Any Minute Now are revisited in a dance key, but above all the long journey of the Two Many DJs, namely the two Dewaele brothers who try their hand at plates mixing tracks of any genre, from Madonna to Nirvana, from Iggy Pop to Salt-n-Pepa, from Beyoncé to LCD Soundsystem.

In 2004 the Italian singer-songwriter Mango performed a cover of their track Saturday, inserting it in the album I'll take you to Africa.

Under the name 2 Many DJs they have made numerous DJ sets and live remixes, then also broadcast on radio programs such as BBC Radio 1. Solo As Heard on Radio Soulwax Pt. 2 It was released as an album, in total there are 11 parts. They made 24 remixes lasting 1 hour each with related videos published on Vimeo and on their smartphone app.